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A prescription-only, high-potency natural progestogen formulation designed for vaginal or rectal administration to support hormonal balance during early pregnancy, fertility treatments, and menstrual health management.
Cyclogest contains Progesterone (400mg), which is chemically identical to the natural hormone produced by a woman’s ovaries during the second half of the menstrual cycle:
Endometrial Preparation: It transforms the inner lining of the uterus (the endometrium) into a thick, nutrient-rich bed, making it receptive for a fertilized egg to attach and grow.
Uterine Relaxation: Progesterone acts as a natural muscle relaxant for the womb. By lowering the contractility of the uterine smooth muscle, it keeps the uterus calm and prevents early contractions.
Pregnancy Maintenance: During fertility cycles or early pregnancy, it provides the essential hormonal baseline needed to support and hold the pregnancy until the placenta develops enough to produce its own progesterone.
Assisted Reproductive Technology (ART): Providing vital luteal phase support for women undergoing fertility procedures like IVF.
Miscarriage Prevention: Supporting women with a history of recurrent miscarriages or managing threatened miscarriages due to documented progesterone insufficiency.
Premenstrual Syndrome (PMS) & Postpartum Depression: Treating severe premenstrual symptoms or depression following childbirth linked to sudden hormone drops.
Undiagnosed Vaginal Bleeding: Do not use if you experience unusual vaginal bleeding that has not been thoroughly evaluated by your gynecologist.
Thromboembolic Disorders: Strictly contraindicated if you have an active blood clot or a history of blood clotting issues (such as deep vein thrombosis, pulmonary embolism, stroke, or heart attack).
Severe Hepatic Dysfunction: Avoid completely if you have severe liver disease or tumors.
Porphyria: Individuals managing this rare inherited blood disorder must not use this medication.
Cyclogest can be inserted either vaginally or rectally. Your doctor will tell you exactly which route to use. Your choice of route depends on specific daily circumstances:
Vaginal Insertion is standardly preferred for fertility treatments and early pregnancy support to deliver the hormone directly to the uterine tissues.
Switch to Rectal Insertion if: You have a vaginal infection, a recently repaired episiotomy from childbirth, severe pelvic floor weakness, or if you are using barrier contraceptives like diaphragms or condoms (the base of the pessary can weaken rubber materials).
1.Wash your hands and unwrap the pessary:Preparation.
Wash your hands thoroughly with soap and water. Tear open the plastic mold strip along the notched V-shape to release one single 400mg waxy pessary.
2.Insert deeply into the vagina if directed:Vaginal Delivery.
If using the vaginal route: Lie down on your back with your knees bent up. Push the tapered end of the pessary as deeply and comfortably as possible into your vagina using your index finger.
3.Insert gently into the rectum if preferred:Rectal Delivery.
If using the rectal route: Lie on your side, pull your top knee up slightly, and gently push the pessary completely through your anal sphincter into your rectum.
4.Lie flat for 15 to 30 minutes and wash hands:Absorption Lock.
Remain lying completely flat for 15 to 30 minutes after insertion. This lets the waxy base melt comfortably so the hormone absorbs fully without leaking out. Wash your hands thoroughly.
Because the pessary uses a vegetable-oil base to carry the progesterone, the wax will melt entirely inside your body. It is completely normal to notice a small amount of white, oily discharge or leakage a short while after insertion. Wearing a light panty liner protects your clothing and keeps you comfortable.
Localized changes depending on the route, such as mild vaginal itching/discharge, or rectal soreness, flatulence (gas), and mild diarrhea when used rectally.
Central nervous system variations, including brief sleepiness, dizziness, or a mild headache shortly after insertion.
Cyclical shifts, including breast tenderness, a feeling of bloating, hot flushes, or acne breakouts early in the treatment course.
What should I do if I accidentally miss a scheduled dose?
If you forget to insert your pessary, take it as soon as you remember. However, if it is almost time for your next regular dose, skip the missed pessary entirely and continue with your normal schedule. Do not insert a double dose to catch up.
Can I use anti-fungal creams alongside Cyclogest vaginal pessaries?
If you develop a vaginal yeast infection while using Cyclogest, talk to your doctor before applying local anti-fungal treatments. Using multiple vaginal creams or suppositories at the same time can interfere with how well the progesterone dissolves and absorbs. Your doctor may suggest temporarily switching your Cyclogest to the rectal route.
How should I store my Cyclogest pessaries in hot weather?
Pessaries are made of wax designed to melt at human body temperature ($37^\circ\text{C}$). In hot climates like Nigeria, store your box in a cool, dry place below 25°C, or keep it inside your refrigerator's vegetable compartment during intense heat waves to prevent the pessaries from softening inside the foil.
Hormone medications require strict storage and supply-chain integrity to prevent degradation. You can purchase genuine, factory-sealed boxes of Cyclogest 400mg Pessaries (commonly available in standard packs of 15 or 30 pessaries) online through Sanlive Pharmacy & Stores for secure payment and fast, reliable same-day delivery directly to your home, office, or clinic within Lagos, Abuja, and Port Harcourt. We also offer nationwide and international deliveries through our trusted logistics partners to ensure your fertility and pregnancy support reaches you safely wherever you are.
Important Notice: This information is for educational support purposes only. Cyclogest is a high-potency, prescription-only hormonal medication. Treatment plans must be started, timed, and monitored exclusively under the direct guidance of a registered obstetrician, gynecologist, or fertility specialist. If you experience sudden chest pain, unexplained shortness of breath, sudden severe leg swelling, or heavy visual changes, stop using the medicine and seek immediate emergency medical evaluation.
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