Avicef Injection (Ceftriaxone Sodium 1g / Avicef Forte)

Avicef Injection is a prescription-only broad-spectrum cephalosporin antibiotic. Depending on the specific formulation (such as standard Avicef or Avicef Forte), it contains Ceftriaxone Sodium (equivalent to 1g of Ceftriaxone) either alone or combined with Sulbactam (as a 1g/500g combination).

It is supplied as a sterile dry powder in a vial accompanied by a diluent (such as Water for Injection or Lidocaine) and is indicated for the treatment of severe bacterial infections, including:

• Lower respiratory tract infections (like pneumonia and bronchitis)

• Complicated urinary tract infections (UTIs) and kidney infections

• Pelvic inflammatory and gynecological diseases

• Intra-abdominal infections, skin/soft tissue infections, and bone/joint infections

• Sepsis, meningitis, and surgical prophylaxis

How It Works

• Ceftriaxone: A third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis, causing cell lysis and death across a broad spectrum of Gram-positive and Gram-negative bacteria.

• Sulbactam (in Forte/Combiformulations): Added to inhibit beta-lactamase enzymes produced by resistant bacteria, protecting ceftriaxone from degradation and expanding its bactericidal range.

Important Safety Warnings

🚨 Cephalosporin & Penicillin Allergy Alert:

Severe Hypersensitivity: Do not use Avicef if there is a known history of severe allergic reactions (anaphylaxis) to ceftriaxone, other cephalosporins, or penicillins. Seek immediate medical care if a rash, swelling, or breathing difficulty occurs.

🚨 Calcium Solution Incompatibility (IV):

Fatal Precipitation Risk: Ceftriaxone must not be mixed or co-administered simultaneously with calcium-containing intravenous solutions (such as Ringer's or Hartmann's solutions) via the same IV line, particularly in neonates.

How to Administer

• Route of Administration: Administered strictly via Intramuscular (IM) injection (when prepared with a local anesthetic like lidocaine) or Intravenous (IV) injection/infusion by a qualified healthcare professional.

• Standard Adult Dosing:

  • Typically ranges from 1g to 2g once daily (or split into two equal doses every 12 hours), depending on the severity and type of infection.

Possible Side Effects

Avicef is generally well-tolerated under clinical supervision. Potential side effects include:

• Pain, tenderness, or swelling at the injection site.

• Mild diarrhea, loose stools, or nausea.

• Temporary changes in liver function tests or blood cell counts.

• Mild skin rash or itching.

How to Store

• Store dry powder vials below 30°C in a dry place protected from light.

• Once reconstituted, the solution should be used immediately.

• Keep strictly out of reach of children.

Frequently Asked Questions (FAQs)

1. Can Avicef Injection be self-administered at home?

No. Avicef is an injectable prescription antibiotic that must be prepared and administered exclusively by a trained nurse or physician in a clinical or hospital environment.

2. Why does the pack sometimes include Lidocaine?

The ampoule of 1% Lidocaine Hydrochloride included in specific combipacks is used strictly as a diluent for intramuscular (IM) injections to minimize injection-site pain. It must never be given intravenously.

Where to Buy Genuine Avicef & International Delivery

You can order verified, original prescription injectables like Avicef Injection directly online from Sanlive Pharmacy & Stores with a valid medical prescription.

We offer fast, secure delivery across Nigeria, as well as international shipping to the UK, US, Europe, Middle East, and other parts of the world.

Notice: This guide is for simple educational information only. Avicef is a prescription-only injectable medicine and must be administered under the direct supervision of a licensed healthcare provider.