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Fleming 457mg is a prescription-only broad-spectrum combination antibiotic (commonly known as Co-Amoxiclav). Each 5ml of the reconstituted oral suspension contains 400mg of Amoxicillin (as Amoxicillin Trihydrate) and 57mg of Clavulanic Acid (as Potassium Clavulanate).
It is widely prescribed for both children and adults to treat various bacterial infections, including:
Respiratory Tract Infections (such as community-acquired pneumonia, acute bronchitis, and sinusitis)
Middle Ear Infections (Otitis Media)
Urinary Tract Infections (UTIs)
Skin and Soft Tissue Infections
Dental Infections
Fleming combines a penicillin antibiotic with a protective beta-lactamase inhibitor:
Amoxicillin: Inhibits bacterial cell wall synthesis, causing cell death across a broad range of Gram-positive and Gram-negative bacteria.
Clavulanic Acid: A beta-lactamase inhibitor that prevents resistant bacteria from destroying amoxicillin, significantly widening its spectrum of effectiveness.
Severe Hypersensitivity: Do not use Fleming if there is a known history of severe allergic reactions (anaphylaxis, angioedema) to amoxicillin, clavulanic acid, penicillin, or cephalosporin antibiotics. Seek immediate emergency medical attention if a rash, facial swelling, or breathing difficulty develops.
Resistance Prevention: Always finish the entire prescribed course of treatment (typically 5 to 10 days), even if symptoms improve within the first few days. Stopping early can cause the infection to return and promote antibiotic resistance.
Excipient Notice: Fleming suspension contains aspartame as a sweetener (a source of phenylalanine), which can be harmful to individuals born with phenylketonuria.
Reconstitution (Mixing the Dry Powder):
Tap the bottle lightly to loosen the dry powder.
Add clean, boiled and cooled water up to the mark on the bottle label in two stages, shaking thoroughly after each addition until completely mixed.
Standard Pediatric Dosing:
Dosing is calculated strictly based on the patient's body weight and infection severity (typically expressed as mg/kg/day divided into two doses every 12 hours). Always follow your doctor's specific prescription.
How to Take:
Shake the bottle well before every single dose.
Use the provided calibrated measuring oral syringe or spoon to ensure accurate dosing.
Take at the start of a meal or with food to maximize absorption and minimize mild gastrointestinal upset.
Common side effects are usually mild and temporary:
Diarrhea or loose stools
Nausea or vomiting
Mild skin rash or itching
Oral or vaginal thrush (candidiasis) due to changes in normal flora
Dry Powder (Before Mixing): Store in a cool, dry place below 30°C away from direct sunlight.
Reconstituted Suspension: Must be stored in a refrigerator (2°C to 8°C) and discarded after 7 to 14 days (check specific manufacturer guidelines on the label).
Keep strictly out of reach of children.
Yes. Taking Fleming at the start of a meal or with food helps reduce stomach upset and improves the body's absorption of the medication.
Take the missed dose as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and resume your regular 12-hour dosing schedule. Never double up doses.
You can order verified, original prescription antibiotics like Fleming 457mg Suspension directly online from Sanlive Pharmacy & Stores with a valid prescription.
We offer fast doorstep delivery across Nigeria, as well as international shipping to the UK, US, Europe, Middle East, and other parts of the world.
Notice: This guide is for simple educational information only. Fleming is a prescription-only antibiotic and must be used strictly under the direct guidance of a licensed healthcare provider.
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