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Oframax S 1500mg is a prescription-only broad-spectrum injectable combination antibiotic. Each vial contains 1000mg (1g) of Ceftriaxone (as Ceftriaxone Sodium) and 500mg of Sulbactam (as Sulbactam Sodium), maintaining a 2:1 ratio.
It is indicated for the treatment of severe bacterial infections caused by resistant or beta-lactamase-producing organisms, including lower respiratory tract infections, severe urinary tract infections (UTIs), intra-abdominal infections, skin and soft tissue infections, bone and joint infections, and septicemia.
Oframax S combines a third-generation cephalosporin with a beta-lactamase inhibitor:
Ceftriaxone (Third-Generation Cephalosporin): Binds to penicillin-binding proteins, inhibiting bacterial cell wall synthesis and causing cell death across a wide range of gram-positive and gram-negative bacteria.
Sulbactam (Beta-Lactamase Inhibitor): Irreversibly inactivates beta-lactamase enzymes produced by resistant bacteria, protecting ceftriaxone from degradation and expanding its bactericidal spectrum.
Severe Hypersensitivity: Do not use if you have a known allergy to ceftriaxone, sulbactam, other cephalosporins, or a history of severe allergic reactions (anaphylaxis) to penicillins. Seek emergency medical attention if signs of an allergic reaction occur.
Fatal Precipitation Risk: Ceftriaxone must not be mixed or co-administered with calcium-containing intravenous solutions (such as Ringer's or Hartmann's solution) in the same IV line, especially in neonates, due to the risk of fatal calcium-ceftriaxone precipitate formation in the lungs and kidneys.
Route of Administration: Administered strictly via Intramuscular (IM) injection or Intravenous (IV) infusion by a qualified healthcare professional.
Standard Adult Dosing:
Usual Dosage: 1.5g to 3g daily, given as a single daily dose or divided into two equal doses every 12 hours depending on infection severity.
Preparation: Reconstitute the dry powder with sterile water for injection or compatible local anesthetics (for IM use only, such as 1% Lidocaine).
Oframax S is generally well-tolerated in clinical settings. Side effects may include:
Pain, tenderness, or inflammation at the injection site.
Mild diarrhea, nausea, or loose stools.
Transient changes in liver function tests or blood cell counts.
Store dry powder vials below 30°C in a dry place protected from light.
Once reconstituted, use immediately or store according to strict institutional refrigeration guidelines.
Keep strictly out of reach of children.
No. Oframax S is an injectable prescription antibiotic that must be prepared and administered strictly by a trained healthcare professional in a clinic or hospital setting.
Sulbactam blocks bacterial enzymes (beta-lactamases) that would normally destroy ceftriaxone, allowing the antibiotic to successfully kill resistant bacterial strains.
Youcan order verified, original prescription injectables like Oframax S Injection 1500mg directly online from Sanlive Pharmacy & Stores with a valid medical prescription.
We offer fast, secure delivery across Nigeria, as well as international shipping to the UK, US, Europe, Middle East, and other parts of the world.
Notice: This guide is for simple educational information only. Oframax S is a prescription-only injectable medication and must be administered under the direct supervision of a licensed physician.
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