We are your trusted health partner. Local doorstep deliveries is within the hour .We are Licensed and Regulated by the Pharmacist's Council of Nigeria(PCN).Prices displayed here may differ due to inflation.
We are your trusted health partner. Local doorstep deliveries is within the hour .We are Licensed and Regulated by the Pharmacist's Council of Nigeria(PCN).Prices displayed here may differ due to inflation.
Imuran 25mg
CHRONIC HEALTH CONDITIONS

Imuran 25mg

₦75,000 ₦90,000
Manufacturer: Aspen Pharmacare (Global) or GSK

Qty
Share

Imuran 25mg

A potent prescription immunosuppressant medication used to reduce the body's natural defense mechanisms, helping to prevent organ transplant rejection and manage severe autoimmune diseases.

 

What It Does

Imuran contains azathioprine (25mg) as its active therapeutic agent. It functions systemically as an antimetabolite and immunosuppressive drug. Once ingested, it is rapidly converted in the body into 6-mercaptopurine, which interferes with the synthesis of DNA and RNA.

By acting as a false building block during cellular replication, it specifically targets and suppresses rapidly dividing cells, particularly T-lymphocytes and B-lymphocytes (white blood cells). By putting the brakes on these overactive immune cells, the medication prevents them from attacking foreign tissues (like a transplanted kidney) or healthy bodily structures (in autoimmune flares).

What It Is Used For

  • Organ Transplant Rejection Prevention: Used in combination with other immunosuppressive therapies to prevent the body from rejecting transplanted kidneys, hearts, or livers.

  • Severe Rheumatoid Arthritis Management: Reducing severe pain, joint swelling, and structural tissue damage when standard disease-modifying therapies have failed.

  • Inflammatory Bowel Disease (IBD) Control: Inducing and maintaining symptom remission in moderate-to-severe Crohn’s disease and ulcerative colitis.

  • Other Autoimmune Conditions: Treating conditions where the immune system attacks itself, such as systemic lupus erythematosus (SLE), severe dermatomyositis, and autoimmune hepatitis.

Who It Is For (And Who Should Avoid It)

✅ Who Can Use It

Adults and specific pediatric populations who have been thoroughly evaluated by a specialist (such as a rheumatologist, gastroenterologist, or transplant surgeon) and prescribed azathioprine therapy.

❌ When to Avoid It

  • Pregnancy and Breastfeeding: Strictly avoided during pregnancy unless the clinical benefits outbalance the severe risks, as it can cause fetal harm. It should not be used while breastfeeding because the drug passes into breast milk.

  • Hypersensitivity to Azathioprine: Strictly contraindicated if you carry a known history of immediate allergic reactions to azathioprine or 6-mercaptopurine.

  • TPMT Deficiency: Individuals with a genetic deficiency in the enzyme thiopurine methyltransferase (TPMT) are at an exceptionally high risk of developing severe, life-threatening bone marrow toxicity from standard doses.

How to Use It Safely

  • The Schedule: Take your tablets orally one to two times daily, exactly as prescribed by your medical specialist. Your doctor will calculate your dosage based on your precise body weight.

  • The Food Law: Take your tablets with or immediately after a meal to reduce potential gastrointestinal upset. Consistency is vital; pick a routine and take it the exact same way each day.

  • The Handling Rule: Do not break, crush, split, or chew the tablets. The dust from damaged tablets can be hazardous if inhaled or absorbed through the skin, especially for women who are pregnant or planning to become pregnant.

Step-by-Step Administration Protocol

 

1.Confirm your exact tablet count:Dose Verification.

Look closely at your clinical prescription. Because Imuran requires highly personalized dosing, ensure the number of 25mg tablets you count matches your current doctor-approved plan.

2.Swallow the tablet whole with a meal:Ingestion Mechanics.

Swallow the tablet completely whole with a full glass of plain water during or right after breakfast or dinner. Do not bite, chew, or allow the tablet to dissolve in your mouth.

3.Attend all scheduled blood monitoring visits:Laboratory Tracking.

Keep every scheduled appointment for blood tests. Your doctor will run regular Complete Blood Counts (CBC) and liver function tests to monitor your bone marrow health.

4.Practice proactive hygiene and safety protocols:Infection Defense.

Wash your hands frequently and avoid close contact with individuals suffering from contagious infections (like flu or chickenpox), as your immune defenses will be lowered.

 

What to Expect: Gradual Therapeutic Onset

Imuran does not provide an immediate, overnight shift in your symptoms. Because it takes time to slow down white blood cell replication cycles, you can expect a progressive reduction in joint pain, bowel inflammation, or autoimmune flares over several weeks. It typically takes six to twelve weeks of continuous daily compliance to experience the full therapeutic benefits of this medication.

Warning: Seek immediate emergency medical attention if you develop signs of a severe infection (such as a high fever, persistent sore throat, or chills), uncharacteristic bruising, blood in your urine, or a sudden yellowing of your skin and eyes.

Possible Side Effects

Because it temporarily dampens the active cellular turnover within your bone marrow and immune pathways, Imuran can occasionally lead to systemic adjustments, including:

  • Increased susceptibility to viral, bacterial, and fungal infections due to lowered white blood cell counts (leukopenia).

  • Mild gastrointestinal changes, such as temporary nausea, vomiting, or a temporary loss of appetite, which usually ease as your body adjusts.

  • Reversible hair thinning, skin rashes, or a mild elevation in liver enzymes.

Frequently Asked Questions

Can I receive my routine vaccinations while undergoing treatment with Imuran?

You should completely avoid receiving any "live" vaccines (such as the yellow fever, MMR, or oral typhoid vaccines) while taking this medication. Because Imuran dampens your immune system, a live vaccine can cause a severe infection. Inactivated or booster vaccines are generally safe, but always consult your doctor before receiving any shot.

What should I do if I take gout medications like allopurinol alongside Imuran?

Inform your doctor immediately if you are taking allopurinol. Allopurinol strongly blocks the metabolism of azathioprine, which can cause a rapid, dangerously toxic buildup of Imuran in your body. If they must be used together, your doctor will drastically reduce your Imuran dosage (often by 50% to 75%) and monitor your blood panels heavily.

What should I do if I accidentally forget to take my scheduled daily dose?

If you remember within a few hours of your regular time, take your dose with food immediately. If it is already close to your next scheduled dose, skip the missed one entirely and resume your standard tracking routine. Do not take a double dose to make up for a forgotten tablet.

Where to buy Imuran 25mg online in Nigeria?

You can purchase authentic Imuran 25mg online through Sanlive Pharmacy & Stores for secure payment and fast, reliable same day delivery within Lagos, Abuja and Port Harcourt.

Important Notice: This is for informational purposes only and is not to be taken as a prescription. Consult a healthcare professional before proceeding with this medication.

No reviews yet — be the first!

Log in to write a review.