We are your trusted health partner. Local doorstep deliveries is within the hour .We are Licensed and Regulated by the Pharmacist's Council of Nigeria(PCN).Prices displayed here may differ due to inflation.
.jpg)
Luprodex 3.75mg is a prescription-only, high-potency gonadotropin-releasing hormone (GnRH) agonist. It contains Leuprolide Acetate (3.75mg) formulated as a sustained-release micro-suspension.
It is administered as an injection exactly once every 4 weeks (28 days). It acts directly on the brain's hormone signaling pathways to down-regulate and temporarily switch off the body's natural production of sex hormones (testosterone in men and estrogen in women).
Luprodex alters the body’s hormonal architecture through a deliberate, two-phase process:
The Initial Surge (The 1st Week): When first injected, the leuprolide molecules over-stimulate the pituitary gland, causing a brief spike in luteinizing hormone (LH) and follicle-stimulating hormone (FSH). This triggers a temporary, transient rise in circulating testosterone or estrogen levels.
The Down-Regulation Blockade (Continuous Phase): After a week of continuous contact, the pituitary gland's receptors switch off entirely. This shuts down LH and FSH secretion, dropping sex hormones to near-zero (castrate baseline in men and menopausal baseline in women).
Starves Target Conditions: Deprived of the hormonal fuel they need to expand, hormone-driven malignant cells stop multiplying, endometrial patches break down, and fibroid masses shrink.
Advanced Prostate Cancer: Long-term management of locally advanced or metastatic prostate cancer, serving as a highly effective medical alternative to surgical removal of the testicles (castration).
Endometriosis: Treating tissue resembling the womb lining that grows outside the uterus, reducing chronic pelvic inflammation and severe menstrual pain.
Uterine Fibroids Preoperative Management: Shrinking non-cancerous muscle tumors in the womb over 3 to 4 months to reduce their overall mass and minimize bleeding complications before a scheduled surgery.
Breast Cancer Support: Adjuvant treatment in pre- and peri-menopausal women with hormone-responsive breast cancer, standardly combined with oral companion therapies (like Tamoxifen or an aromatase inhibitor).
During the first 1 to 2 weeks of starting Luprodex, the initial spike in testosterone can cause a brief worsening of prostate cancer symptoms. This can manifest as increased bone pain, difficulty urinating, or spinal cord pressure. To prevent this, oncologists standardly prescribe an oral anti-androgen pill (such as Casodex/Bicalutamide) to be taken daily starting a few days before your first injection to act as a protective barrier.
Because sex hormones keep bones strong, suppressing them causes temporary bone thinning (osteoporosis). For benign gynecological conditions like endometriosis or fibroids, Luprodex therapy is strictly limited to a maximum of 6 months. Specialists often co-administer a low-dose "add-back" Hormone Replacement Therapy (HRT) to protect your skeletal matrix and ease menopausal side effects.
Unexplained or undiagnosed abnormal vaginal bleeding.
Pregnancy and Breastfeeding: Luprodex is strictly contraindicated. Pregnancy must be completely ruled out before starting treatment, and therapy in women must begin during the first 5 days of their menstrual cycle. Non-hormonal barrier birth control (like condoms) must be used throughout the course.
Strictly Professional Use Only: Luprodex 3.75mg is supplied as a dry powder vial with a companion ampoule of liquid solvent. It can be injected either subcutaneously (under the skin) or deep intramuscularly (into the muscle), and must only be prepared and administered by a qualified healthcare professional.
Immediate Injection Rule: Because this is a microcapsule suspension, the dry powder must be mixed gently with the solvent and injected immediately. If administration is delayed by even a few minutes, the microscopic particles will settle or clump together, completely clogging the needle.
Vary the Injection Site: For long-term treatment lines, the injection location must be rotated periodically to prevent localized skin tissue thickening.
As your system adjusts to the near-total suppression of reproductive hormones, you will experience typical hormonal updates:
In Men: Frequent hot flushes, sudden sweating, temporary erectile dysfunction, a reduction in testicle size, and temporary bone or joint pain during the first 2 weeks.
In Women: Hot flushes, night sweats, pronounced vaginal dryness, mood shifts, anxiety, temporary headaches, and unexpected breakthrough spotting or vaginal bleeding during the first month before periods fully cease.
Localized minor bruising, redness, or a brief dull ache where the needle entered.
What happens if I delay my 4-weekly Luprodex injection by a few days?
To maintain a steady, unyielding block against hormone production, you must receive your injection precisely every 28 days. If you miss your scheduled date, your hormone levels can begin to rebound rapidly, which can cause your symptoms to flare back up or lower the effectiveness of your therapy. Contact your clinic immediately to get your routine back on track.
Can Luprodex affect my blood sugar or heart health?
Yes. Long-term hormone deprivation therapy can cause metabolic shifts, including a reduction in sugar tolerance (potentially worsening diabetes) and minor increases in blood pressure or cholesterol levels. If you have diabetes, you should increase the frequency of your blood glucose monitoring at home and share your logs with your physician.
How should this injection kit be stored before my clinic appointment?
Keep your unopened Luprodex box stored inside a cool, dry room strictly below 25°C and away from direct sunlight. Do not store it in a refrigerator or freezer. Freezing can permanently damage the sustained-release microcapsules and render the solution ineffective.
Advanced endocrine and oncological micro-suspensions require absolute supply chain integrity, strictly regulated storage parameters ($<25^{\circ}\text{C}$), and professional batch tracking to guarantee therapeutic delivery and protect patient outcomes. You can submit your specialist’s medical prescription and purchase genuine, factory-authenticated Luprodex 3.75mg Vials online through Sanlive Pharmacy & Stores for secure payment and fast, reliable same-day delivery directly to your home, office, or specialist clinic within Lagos, Abuja, and Port Harcourt. We also provide nationwide delivery through our trusted specialty clinical logistics channels to deliver your essential oncology or reproductive care safely anywhere in Nigeria.
Important Notice: This information is for educational support and clinical procurement purposes only. Luprodex 3.75mg is a high-potency, prescription-only specialized injection. Your entire treatment protocol must be initiated, monitored, and adjusted under the direct care of a registered oncologist, gynecologist, or qualified medical specialist. If you experience sudden chest pain, rapid heart palpitations, signs of a deep vein thrombosis or pulmonary embolism (severe calf pain or sudden shortness of breath), or a severe blistering skin rash, seek immediate emergency medical care at a hospital.
No reviews yet — be the first!
Log in to write a review.
.jpg)
