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Panadol Extra is an over-the-counter enhanced dual-action pain reliever. Each tablet combines two active ingredients: 500mg of Paracetamol (Acetaminophen) and 65mg of Caffeine.
It is formulated for tough, stubborn pain that standard paracetamol alone may not fully relieve, including severe headaches, migraines, toothaches, period pain, backache, and rheumatic/muscle aches, as well as for fever reduction.
Panadol Extra uses a synergistic combination to maximize pain relief:
Paracetamol (500mg): Blocks prostaglandin synthesis in the central nervous system to inhibit pain signals and lower fever.
Caffeine (65mg): Acts as an analgesic adjuvant. It enhances the pain-relieving effect of paracetamol by up to 30%, helping the medicine work more effectively.
Paracetamol Overdose Risk: Never exceed the maximum recommended daily dose (8 tablets / 4000mg paracetamol in 24 hours). Taking too much paracetamol can cause severe, irreversible liver damage.
Avoid Combination Use: Do not take Panadol Extra alongside any other medications containing paracetamol. Limit your intake of caffeinated drinks (coffee, tea, cola, energy drinks) while taking this medication, as excessive caffeine can cause nervousness, irritability, sleeplessness, and a rapid heartbeat.
Recommended Dosage for Adults and Adolescents (Aged 12 Years & Older):
Take 1 to 2 tablets every 4 to 6 hours as needed.
Maximum dose: 8 tablets in any 24-hour period.
Age Limit: Do not give to children under 12 years of age.
How to Take:
Swallow tablets whole with a glass of water.
Can be taken with or without food.
Leave at least 4 hours between doses.
Panadol Extra is well-tolerated when taken as directed. Side effects are typically related to the caffeine content and may include:
Mild restlessness, nervousness, or difficulty sleeping (insomnia).
Increased heart rate or mild dizziness.
Mild stomach discomfort.
Store in a cool, dry place below 30°C.
Keep tablets inside their original blister packaging to protect from moisture and light.
Keep strictly out of reach of children.
Regular Panadol contains only paracetamol (500mg). Panadol Extra includes 65mg of caffeine per tablet, which boosts the pain-relieving power of paracetamol, making it ideal for tougher pain like severe headaches or migraines.
Panadol Extra is generally not recommended during pregnancy due to the caffeine content, which may increase the risk of lower birth weight or spontaneous abortion. Pregnant women are advised to use standard paracetamol (without caffeine). If breastfeeding, consult your healthcare provider before use.
Yes, if necessary. Paracetamol with caffeine and ibuprofen belong to different drug classes and can be taken together or alternated, provided you do not exceed the daily limits for either medicine.
You can order verified, original healthcare products like Panadol Extra Tablets directly online from Sanlive Pharmacy & Stores.
We offer fast doorstep delivery across Nigeria, as well as international shipping to the UK, US, Europe, Middle East, and other parts of the world.
Notice: This guide is for simple educational information only. Always read the packaging leaflet carefully. If pain or fever persists for more than 3 days, consult a physician or pharmacist.
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